Corona Virus( COVID-19) Top Vaccine Candidates
Ever since COVID-19 outbreak, laboratories around the world have been busy creating vaccines and undergoing trials.
Several companies and governments doubled their efforts to find a permanent cure.
Apart from individual progression, world leaders and organizations, excluding the United States pledged $ 8 billion to research, manufacture and distribute a vaccine and treatment for the virus.
![]() |
Here are some of the top vaccine candidates
Ad5nCoV Vaccine
• Adenovirus Type 5 Vector, an advanced DNA vaccine is named as the top contender for COVID-19 by the WHO.
• It's developed by using both Chinese and Canadian technology and is Co-developed by the Beijing Institute of Biotechnology Biologics Inc. (BIB) and CanSino Genetically engineered defective adenovirus type 5 vector was replication used to express the SARS-CoV-2 spike protein which is grown using living cells.
Remdesivir Vaccine
• Dr. Anthony Fauci of National Institute of Allergy and Infectious Diseases (NIAID) said that the trial for Remdesivir produced a 'clear cut positive effect in diminishing time to recover.
• Vaccinated people had recovered from COVID-19 in just 11 days compared to the control group that took 15 days.
• Remdesivir has shown promising results in the treatment of other coronavirus diseases such as SARS and MERS.
AZD1222 VACCINE
• This vaccine is being developed by Oxford University and supported by the British Pharma company, Astrazeneca.
• The company stated that it would roll out up to 2 billion doses in September.
• The vaccine uses a replication-deficient chimpanzee viral vector based on a weakened version of a common cold (adenovirus) virus that causes infections in chimpanzees. It has been modified to work on humans and contains the genetic material of SARS-COV-2 spike protein.
• The vaccine has already progressed into phase II / III trials involving 10,000 people from the UK.
MRNA-1273 Vaccine
• This experimental vaccine is created by one of the leading US companies, Moderna Inc.
• The vaccine has received approval from the FDA to proceed with the phase II clinical trial.
• The phase II trial will evaluate the safety and immunogenicity of two MRNA-1273 vaccinations.
Inovio's Vaccine
• Before the outbreak, the company was in the process of creating a DNA vaccine for MERS. Resultantly, developed a potential vaccine for SARS- the company swiftly CoV-2.
• The vaccine (INO-4800) targets the Spike protein, a surface antigen that causes COVID-19.
• Phase II / II clinical trials will take place this summer.
READ ALSO:
Trump Ruling Discriminates Against Transgender People; Erases Transgender Civil Rights Protections In Health Care
Right Upto The Global Ventilator Challenge In Amid Covid -19
What are some things people should do/follow in their daily lives to protect the environment/nature?
SANOFI'S VACCINE
• Sanofi is developing COVID-19 vaccine with GlaxoSmithKline and Translate Bio.
• GSK's proprietary adjuvants are being used, which is a compound that boosts immune response, allowing less vaccine to be used for each person.
• Sanofi predicts to get approved by the FDA soon and states that Phase III trial for the vaccine could begin in December or January, 2021.
• Sanofi and Translate Bio have multiple MRNA vaccine candidates against COVID-19 in preclinical testing and will start a first human trial in the fourth quarter of this year.
0 comments:
Post a comment